7
Oct
2026
Epileptogenic Drugs and lifestyle in clinical psychiatric practice
Posted On October 7, 2026
By [email protected]
And has No Comment
- Defining seizure activity (Slide 2) — from subclinical EEG paroxysms and myoclonus to focal and generalized tonic-clonic seizures.
- Historical part (Slide 3) — Von Meduna’s 1934 chemical convulsive therapy (camphor and Metrazol) through to modern psychopharmacology.
- Epileptogenic drugs by class (Slides 5–7) — antipsychotics (Clozapine, Chlorpromazine), antidepressants (Bupropion, Maprotiline, Clomipramine), lithium toxicity, Tramadol, fluoroquinolones, carbapenems.
- Epileptogenic foods/supplements (Slide 8) — Ginkgo biloba, starfruit, camphor/essential oils, high-dose caffeine, versus the ketogenic diet.
- Relation to ECT (Slide 9) — seizure threshold, clozapine reduction during ECT, caffeine augmentation.
- How to avoid harm (Slides 10–11) and how to use them beneficially (Slide 10) — slow titration, prophylactic valproate/lamotrigine, safe dose ceilings.
- Emergency management (Slide 12) — status epilepticus protocol and post-ictal re-challenge.
