Dopamine High dose
What is dopamine?
Dopamine is a medication form of a substance that occurs naturally in the body. It works by improving the pumping strength of the heart and improves blood flow to the kidneys.
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- Dopamine Injection
Dopamine Injection
Generic Name: dopamine (injection) (DOE pa meen)
Brand Names: Intropin
What is dopamine?
Dopamine is a medication form of a substance that occurs naturally in the body. It works by improving the pumping strength of the heart and improves blood flow to the kidneys.
Dopamine injection (Intropin) is used to treat certain conditions that occur when you are in shock, which may be caused by a heart attack, trauma, surgery, heart failure, kidney failure, and other serious medical conditions.
Dosage Forms & Strengths
infusion solution, in D5W
- 80mg/100mL
- 160mg/100mL
- 320mg/100mL
injectable solution
- 40mg/mL
- 80mg/mL
- 160mg/mL
Hemodynamic Conditions
Treatment of hypotension, low cardiac output, poor perfusion of vital organs; used to increase mean arterial pressure in septic shock patients who remain hypotensive after adequate volume expansion
1-5 mcg/kg/min IV (low dose): May increase urine output and renal blood flow
5-15 mcg/kg/min IV (medium dose):
May increase renal blood flow, cardiac output, heart rate, and cardiac contractitlity
Dosing:
20-50 mcg/kg/min IV (high dose): May increase blood pressure and stimulate vasoconstriction; may not have a beneficial effect in blood pressure; may increase risk of tachyarrhythmias
May increase infusion by 1-4 mcg/kg/min at 10-30 min intervals until optimum response obtained
Titrate to desired response
Dosing Considerations
Strong beta1-adrenergic, alpha-adrenergic, and dopaminergic effects are based on dosing rate
Beta1 effects: 2-10 mcg/kg/min
Alpha effects: >10 mcg/kg/min
Dopaminergic effects: 0.5-2 mcg/kg/min
